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DeCS
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Descriptor English:
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Receptors, Vascular Endothelial Growth Factor
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Descriptor Spanish:
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receptores del factor de crecimiento del endotelio vascular
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Descriptor Portuguese:
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Receptores de Fatores de Crescimento do Endotélio Vascular
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Synonyms English:
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Endothelial Growth Factor Receptor
Receptor, Endothelial Growth Factors
Receptor, Vascular Endothelial Cell Growth Factor
Receptor, Vascular Permeability Factor
Receptors, VEGF
VEGF Receptor
VEGF Receptors
VPF Receptor
Vascular Endothelial Cell Growth Factor Receptor
Vascular Endothelial Growth Factor Receptor
Vascular Permeability Factor Receptor
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Tree Number:
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D08.811.913.696.620.682.725.400.950
D12.776.543.750.630.750
D12.776.543.750.750.400.910
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Definition English:
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A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular IG-LIKE DOMAINS which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels. |
Indexing Annotation English:
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general; prefer specifics
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See Related English:
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Bevacizumab
Immunoglobulin Domains
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History Note English:
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2003; use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1991-2002; for ENDOTHELIAL GROWTH FACTOR RECEPTOR use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1985-2003
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Allowable Qualifiers English:
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Record Number:
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37357
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Unique Identifier:
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D040262
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Occurrence in VHL:
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Similar:
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DeCS
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